A novel Arabidopsis receptor kinase mediating oligogalacturonide-triggered immunity and disease resistance
Klara Culjak (Spain)1 2; Jana Ordon (Switzerland)3; Owen Kendish (Switzerland)4; Marina Martín-Dacal (Spain)1 2; Miguel Angel Torres (Spain)1 2 5; Meriem Aitouguinane (Spain)1; Vicente Ramírez (Germany)6; Lu Zhang (China)5 7; Diego José Berlanga (Spain)1 2 5; Gemma López (Spain)1; Kyle Bender (Switzerland)3; Alberto Macho (China)5 7; Markus Pauly (Germany)6; Antonio Molina (Spain)1 2 5; Julia Santiago (Switzerland)4; Cyril Zipfel (Switzerland)3 8; Lucía Jordá (Spain)1 2 5;
1 - Centro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA)/Consejo Superior de Investigaciones Científicas (CSIC), 28223 Pozuelo de Alarcón (Madrid), Spain; 2 - Departamento de Biotecnología-Biología Vegetal, Escuela Técnica Superior de Ingeniería Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, 28040 Madrid, Spain; 3 - Institute of Plant and Microbial Biology, University of Zürich, 8008 Zürich, Switzerland; 4 - Department of Plant Molecular Biology, University of Lausanne, 1015 Lausanne, Switzerland; 5 - Center of Excellence for Plant-Environment Interactions (CEPEI), CBGP-CEMPS; 6 - Institute of Plant Cell Biology and Biotechnology, Heinrich Heine University, 40225 Düsseldorf, Germany; 7 - Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences (CEMPS), Chinese Academy of Sciences (CAS), 201602 Shanghai, China; 8 - The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, NR47UH Norwich, UK;
Keywords: receptor; oligogalacturonides; immunity;
Abstract Topics: Theme 9: Cell Wall Function and Signaling in plant adaptation to Biotic and Abiotic Stresses
Type of Presentation: Oral Communication
Abstract text: Plants are exposed to pathogens and pests, with the cell wall acting as an initial barrier against these threats. When damaged by pathogens, fragments are released from the cell wall that act as damage-associated molecular patterns (DAMPs), activating pattern-triggered immunity (PTI). Oligogalacturonides (OGs), derived from cell wall pectins, are among the most studied DAMPs, yet their receptor remains unknown. Although pectin-binding receptor kinases of the WALL-ASSOCIATED KINASE (WAK) family were proposed as OG receptors, Arabidopsis mutants lacking all five WAK1-WAK5 genes show wild type-like immune responses to OGs. We have identified the Arabidopsis REDUCED SENSITIVITY TO OGs 1 (RSO1) as a key receptor kinase required for OG-triggered responses. The rso1 mutant exhibits impaired PTI to OGs with higher degrees of polymerization (DPs). In contrast, perception of lower-DP OGs is independent of, or only partially dependent on, RSO1, indicating that OGs of different DPs are recognized by distinct receptors. RSO1 is not required for responses to other elicitors, including CEL3, CHI6, and flg22. rso1 plants show increased susceptibility to different pathogens like Plectosphaerella cucumerina, Pseudomonas syringae, and Ralstonia solanacearum. These data support a central role of RSO1 in OG perception and highlight its potential for developing sustainable crop protection strategies.